Advice for healthcare professionals to provide to patients and caregivers:

  • Methotrexate treatment may make your skin more sensitive to the sun.
  • Sun exposure during methotrexate treatment could cause very severe reactions that look and feel like sunburn.
  • Avoid exposure to intense sunlight (especially between 11 am and 3 pm) or to UV rays (for example, using sunbeds or tanning equipment) while taking methotrexate
  • Use a sun protection product with a high protection factor when exposed to the sun
  • Wear a hat and clothes that cover your arms and legs when in the sun
  • Talk to a healthcare professional if you are worried about a skin reaction you have had while taking methotrexate.